Interleukin 2-induced proliferation of leukemic human B cells.

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Interleukin 2-induced proliferation of leukemic human B cells

The proliferative responses of purified leukemic human B cells from nine B cell chronic lymphocytic leukemias to recombinant interleukin 2 (IL-2), spontaneously, and after preactivation by Staphylococcus aureus Cowan I (SAC) or anti-mu antibodies were studied. Three patterns of response were observed: (a) no response (three cases); (b) a moderate spontaneous response enhanced by anti-mu (one ca...

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ژورنال

عنوان ژورنال: Journal of Experimental Medicine

سال: 1985

ISSN: 0022-1007,1540-9538

DOI: 10.1084/jem.161.5.1225